FAQs 

Who is funding the project and the clinical trial?

This clinical trial is funded by a $4.4 million grant from the Department of Defense (DoD) Congressionally Directed Medical Research Programs (CDMRP), Multiple Sclerosis Research Program (MSRP).

Why is this research being done?

Fatigue is commonly experienced by people with multiple sclerosis (MS) but there are few treatments available to help with this symptom. The two experimental online programs in this clinical trial for fatigue in MS are being evaluated as possible treatment options. These online programs both contain potentially useful information on MS and fatigue. They differ in some aspects, but both are intended to provide information that could help you understand and manage any fatigue symptoms you are experiencing. Neither of these programs has been approved as a treatment by the Food and Drug Administration (FDA) in the United States. A successful clinical trial may result in the FDA approving one of the online programs for managing fatigue in MS.

Will being in this research benefit me?

We cannot promise any benefits to you or others from your taking part in this research. However, a possible benefit to you is that you may experience a reduction in your fatigue symptoms from participating in this trial.

Could being in this research hurt me?

The most important risks or discomforts that you may expect from taking part in this research include the possible loss of privacy or breach of confidentiality. We will take steps to reduce this risk, such as assigning a de-identified study code to your data that is collected during the course of this trial.

Any psychological risks involved are believed to be minimal; however, you may experience some momentary frustration when attempting to perform tasks during which you experience difficulty. The researchers will try to minimize any frustration that may occur.

Using the online programs associated with this trial and/or completing the outcome questionnaires may worsen your fatigue.

There may be some unanticipated discomforts or risks in addition to those specified above, but every precaution will be taken to assure your personal safety and to minimize any discomforts.

What happens to me if I agree to take part in this research?

If you decide to take part in this research study and are eligible to participate, the general procedures include being randomized to one of three experimental groups, using one or both of the experimental online programs, and submitting responses to online questionnaires through the secure clinical trial website. Your involvement in the clinical trial is expected to last for approximately 12 months. Taking part in this research is voluntary and may leave the study at any time.

Will I be paid for taking part in this research?

If you are eligible for the clinical trial, you will be compensated $15 (paid via a digital or physical gift card) for completing each set of questionnaires at the 8 time-points. You will receive a total of $120 if you complete all the questionnaires.